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KMID : 0978920030040020005
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Korean Journal of Clinical Geriatrics
2003 Volume.4 No. 2 p.5 ~ p.15
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A Clinical Study in the elderly with Hyperferritinemia and Anemia associated diseases
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Lee Jong-Hwa
Hahn Jee-Sook
Ko Yun-Woong
Song Kyung-Soon
Won Dong-Il
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Abstract
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Background: Hyperferritinemias are frequently found in the iron study for the elderly patient with anemia associated diseases. We wanted to evaluate clinical significance of hyperferritinemias.
Methods: Firty eight elderly patients with hyperferritinemia (ferritin > 500ng/mL) between May 2000 and Ap피 2001 at Youngdong Severance Hospit떠 were identified with reviews of medical records.
Results: Hyperferritinemias with decreased serum iron, UIBC and TIBC were found in 8 patients with solid tumors and 17 patients with chronic infection or inflammations. Hyperferritinernias with normal serum iron but decreased UIBC and TIBC were found in 18 patients with chronic renal failure, 3 diabetic patients and 2 patients with blood dyscrasias. Hyperferritinemias with increased serum iron but decreased UIBC and TIBC were found in 3 patients with hemochromatosis or hemosiderosis and 2 patients with chronic liver diseases.
Conc lusion: Hyperferritinemias in the elderly serve as a marker for a variety of clinical conditions and provide insight into the pathogenesis of anemia associated diseases.
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KEYWORD
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Hyperferritinemia, the elderly, UIBC, TIBC, Anemia associated diseases
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